Cisco’s documentation implies that to enable jumbo frames on the 5K and 9K line, one must simply set mtu 9216 on the physical and logical L1/L2 interfaces:

Configure and Verify Maximum Transmission Unit on Cisco Nexus Platforms

However, currently working with the 93180YC-EX and previously worked with the 5672UP, I can tell you that both are actually based on the obscureĀ 6K line.

So, in order to get jumbo frames, you have to do this additional step:

policy-map type network-qos jumbo
  class type network-qos class-default
          mtu 9216
system qos
  service-policy type network-qos jumbo

After applying this, also do a set mtu 9216 on the on the L3 SVIs:

Switch(config)#interface Vlan200
  no shutdown
  mtu 9216

Switch# show interface vl200
Vlan200 is up, line protocol is up, autostate enabled
Hardware is EtherSVI, address is 70ea.1a44.d0a7
Internet Address is 192.168.200.1/24
MTU 9216 bytes, BW 1000000 Kbit, DLY 10 usec,

93180YC – Jumbo Frames